David H. Perlmutter, M.D.

David H. Perlmutter, M.D.

α1-antitrypsin deficiency, protein secretion, protein degradation, autophagy, proteostasis, autophagy enhancer drugs

Executive Vice Chancellor for Medical Affairs and Dean
Professor

Pediatrics

Molecular Cell Biology Program
Immunology Program
Molecular Genetics and Genomics Program

  • α1-antitrypsin deficiency, protein secretion, protein degradation, autophagy, proteostasis, autophagy enhancer drugs

  • Pathobiology of liver disease from accumulation and proteotoxicity of misfolded proteins in α1-antitrypsin deficiency; role of autophagy in biology and treatment of disorders caused by misfolded proteins