Eunkyung Yang

Eunkyung Yang

Former Member
Educational Background

 

 

Dr. Yang received her B.S. and M.S. in Chemistry from Kookmin University (Seoul, Republic of Korea). She joined the Holten lab in 2008 and received her Ph.D in Chemistry from Washington University in St. Louis in 2013.

Research Interests

 

 

Dr. Yang's research focuses primarily on the photophysical characterization of synthetic bacteriochlorins using static and time-resolved optical spectroscopy, including measurements of absorption and fluorescence spectra, fluorescence yields, triplet yields, singlet and triplet excited state lifetimes. Specifically, how these properties relate to applications of the bacteriochlorins as photosensitizers for enhanced photodynamic therapy (PDT) and solar-energy conversion is of interest. The studies also encompass energy and electron transfer in tetrapyrrole-based multichromophore arrays. 

Publications

 

 

Integration of Cyanine, Merocyanine and Styryl Dye Motifs with Synthetic Bacteriochlorins, E. Yang, N. Zhang, M. Krayer, M. Taniguchi, J. R. Diers, C. Kirmaier, J. S. Lindsey, D. F. Bocian and D. Holten Photochem. Photobiol. 2016, 92, 111-125.

Synthetic Bacteriochlorins Bearing Polar Motifs (Carboxylate, Phosphonate, Ammonium and a Short PEG). Water-solubilization, Bioconjugation, and Photophysical Properties, J. Jiang, E. Yang, K. R. Reddy, D. M. Niedzwiedzki,  C. Kirmaier, D. F. Bocian, D. Holten and J. S. Lindsey, New J. Chem., 2015, 39, 5694-5714.

Extending the Short and Long Wavelength Limits of Bacteriochlorin Near-Infrared Absorption via Dioxo- and Bisimide-Functionalization, P. Vairaprakash, E. Yang, T. Sahin, M. Taniguchi, M. Krayer, J. R. Diers, A. Wang, D. M. Niedzwiedzki, C. Kirmaier, J. S. Lindsey, D. F. Bocian, and D. Holten, J. Phys. Chem. B, 2015­, 119, 4382-4995.

Probing Electronic Communication for Efficient Light-Harvesting Functionality: Dyads Containing a Common Perylene and a Porphyrin, Chlorin, or Bacteriochlorin, E. K. Yang, J. Wang, J. R. Diers, D. M. Niedzwiedzki, C. Kirmaier, D. F. Bocian, J. S. Lindsey, and D. Holten, J. Phys. Chem. B. 2014, 118, 1630-1647.

Distinct Photophysical and Electronic Characteristics of Strongly Coupled Dyads Containing a Perylene Accessory Pigment and a Porphyrin, Chlorin, or Bacteriochlorin, J. Wang, E.K. Yang, J. R. Diers, D. M. Niedzwiedzki, C. Kirmaier, D. F. Bocian, J. S. Lindsey, and D. Holten, J. Phys. Chem. B., 2013, 117, 9288–9304.

Amphiphilic Chlorins and Bacteriochlorins in Micellar Environments.  Molecular Design, De Novo Synthesis, and Photophysical Properties, K. Aravindu, O. Mass, P. Vairaprakash, J. W. Springer, E. Yang, D. D. M. Niedzwiedzki, C. Kirmaier,  D. F. Bocian, D. Holten, and J. S. Lindsey Chemical Science 2013, 4, 3459–3477.

Molecular Electronic Tuning of Photosensitizers to Enhance Photodynamic Therapy: Synthetic Dicyanobacteriochlorins as a Case Study. E. Yang, J. R. Diers, Y. Y. Huang, K. Aravindu, M. R. Hamblin, J. S.  Lindsey, D. F. Bocian, D. Holten. Photochem. Photobiol. 2013, 89, 605-618.

Palette of Lipophilic Bacteriochlorins for Construction of Biohybrid Light-Harvesting Architectures, K. R. Reddy, J. Jiang, M. Krayer, M. A. Harris, J. W. Springer, E. Yang, J. Jiao, D. M. Niedzwiedzki, D. Pandithavidana, P. S. Parkes-Loach, C. Kirmaier, P. A. Loach, D. F. Bocian, D. Holten, and J. S. Lindsey. Chem. Sci. 2013, 4, 2036-2053.

Photophysical Properties and Electronic Structure of Bacteriochlorin–Chalcones with Extended Near-Infrared Absorption, E. Yang, C. Ruzié, M. Krayer, J. R. Diers, D. M. Niedzwiedzki, C. Kirmaier, J. S. Lindsey, D. F. Bocian, and D. Holten   Photochem. Photobiol. 2013, 89, 586-604.

Synthetic Bacteriochlorins with Integral Spiro-Piperidine Motifs. K. R. Reddy, E. Lubian, M. P. Pavan, H. J. Kim, E. Yang, D. Holten, J. S. Lindsey.  New. J. Chem. 201337, 1157-1173.

Stable Synthetic Bacteriochlorins for Photodynamic Therapy: Role of Dicyano Peripheral Groups, Central Metal Substitution (2H, Zn, Pd), and Cremophor EL Delivery. Y. Y. Huang, T. Balasubramanian, E. YangD. Luo, J. R. Diers, D. F. Bocian, J. S. Lindsey, D. Holten, M. R. Hamblin. ChemMedChem20127, 2155–2167.

Synthesis and Physicochemical Properties of Metallobacteriochlorins. C. Y. Chen, E. Sun, D. Fan, M. Taniguchi, B. McDowell, E. Yang, J. R. Diers, D. F. Bocian, D. Holten, J. S. Lindsey. Inorg.Chem. 201251, 9443–9464.

Photophysical Properties and Electronic Structure of Stable, Tunable Synthetic Bacteriochlorins: Extending the Features of Native Photosynthetic Pigments. E. Yang, C. Kirmaier, M. Krayer, M. Taniguchi, H. J. Kim, J. R. Diers, D. F. Bocian, J. S. Lindsey, D. Holten. J. Phys. Chem. B. 2011, 115, 10801–10816

Synthesis and Photophysical Characterization of Stable Indium Bacteriochlorins, M. Krayer, E. Yang, H-J. Kim, H. L. Kee, R. M. Deans, C. E. Sluder, J. R. Diers, C. Kirmaier, D. F. Bocian, D. Holten, and J. S. Lindsey Inorg. Chem. 2011, 50, 4607-4618. 

 

De Novo Synthesis and Photophysical Characterization of Annulated Bacteriochlorins.  Mimicking and Extending the Properties of Bacteriochlorophylls, M. Krayer, E. Yang, J. R. Diers, D. F. Bocian, D. Holten, and J. S. Lindsey N. J. Chem 2011, 35, 587-601.

 

Excited-State Photodynamics of Perylene–Porphyrin Dyads 5.  Tuning Light-Harvesting Characteristics via Perylene Substituents, Connection Motif and 3-Dimensional Architecture, C. Kirmaier, H. Song, E. Yang, J. K. Schwartz, E. Hindin, J. R. Diers, R. S. Loewe, K-Y Tomizaki,  F. Chevalier, L. Ramos, R. R. Birge, J. S. Lindsey, D. F. Bocian,  and D. Holten  J. Phys. Chem. B. 2010, 114, 14249-14264. 

 

Stable Synthetic Cationic Bacteriochlorins as Antimicrobial Photosensitizers, L. Huang, Y.-Y. Huang, G. P. Tegos, T. Zhiyentayev, S. K Sharma, T. Balasubramian, M. Krayer, C. Ruzié,  E. Yang, H. L. Kee, C. Kirmaier, J. R. Diers, D. F. Bocian, D. Holten, J. S. Lindsey, and M. R. Hamblin  Antimicrobial Agents and Chemotherapy (AAC) 2010, 54, 3834-3841.

 

Stable Synthetic Bacteriochlorins Overcome the Resistance of Melanoma to Photodynamic Therapy P. Mroz, Y.-Y. Huang, S. Janjua, T. Zhiyentayev, A. Szokalska, A-P Nifli, M. Sherwood, C. Ruziée, K. E. Borbas, D. Fan, M. Krayer, T. Balasubramanian, E. Yang, H. L. Kee, C. Kirmaier, J. R. Diers, D. F. Bocian, D. Holten, J. S. Lindsey, and M. R. Hamblin  FASEB J. 2010, 24, 3610-3170. 

 

In vitro Photodynamic Therapy and Quantitative Structure Activity Relationship Studies with Stable Synthetic Near-Infrared-Absorbing Bacteriochlorin Photosensitizers, Y.-Y. Huang, P. Mroz, T. Zhiyentayev, T. Balasubramanian, C. Ruzié, M. Krayer, D. Fan, K. E. Borbas, E. Yang,  H. L. Kee, C. Kirmaier, J. R. Diers, D. F. Bocian, D. Holten, J. S. Lindsey, and M. R. Hamblin J. Med. Chem. 2010, 53, 4018-4027.

 

New stable synthetic bacteriochlorins for photodynamic therapy of melanoma, P. Mroz, Y.-Y. Huang, S. Janjua, T. Zhiyentayev, A. Szokalska, A-P Nifli, M. Sherwood, C. Ruzié, K. E. Borbas, D. Fan, M. Krayer, T. Balasubramanian, E. Yang, H. L. Kee, C. Kirmaier, J. R. Diers, D. F. Bocian, D. Holten, J. S. Lindsey, and M. R. Hamblin Proc of SPIE (Photodynamic Therapy: Back to the Future) 2009, 7380, 73802S-3802S-14.