Rebecca Cahoon

Rebecca Cahoon

Research Associate, 2002-2008
• Staff Scientist, U. Nebraska

Cahoon RE, Lutke WK, Cameron JC, Chen S, Lee SG, Rivard RS, Rea PA, Jez JM (2015) Adaptive engineering of phytochelatin-based heavy metal tolerance.  J Biol Chem 290, 17321-30

Schroeder AC, Zhu C, Yanamadala SR, Cahoon RE, Arkus KAJ, Wachsstock L, Bleeke J, Krishnan HB, Jez JM (2010) Threonine-insensitive homoserine dehydrogenase from soybean: genomic organization, kinetic characterization, and in vivo activity.  J Biol Chem 285, 827-34

Galant A, Arkus KAJ, Zubieta C, Cahoon RE, Jez JM (2009) Structural basis for evolution of product diversity in soybean glutathione synthesis.  Plant Cell 21, 3450-8

Alvarez S, Berla BM, Sheffield J, Cahoon RE, Jez JM, Hicks LM  (2009) Comprehensive analysis of the Brassica juncea root proteome in response to cadmium exposure by complementary proteomic approaches.  Proteomics 9, 2419-31

Schroeder AC, Kumaran S, Hicks LM, Cahoon RE, Halls C, Yu O, Jez JM (2008) Contributions of conserved serine and tyrosine residues to catalysis, ligand binding, and cofactor processing in the active site of tyrosine ammonia lyase.  Phytochemistry 69, 1496-506

Zubieta C, Arkus KAJ, Cahoon RE, Jez JM  (2008) A single amino acid change is responsible for evolution of acyltransferase specificity in bacterial methionine biosynthesis.  J Biol Chem  283, 7561-7

Phartiyal P, Kim WS, Cahoon RE, Jez JM, Krishnan HB (2008) The role of 5’-adenylylsulfate reductase in the sulfur assimilation pathway of soybean:  molecular cloning, gene expression, and kinetic characterization.  Phytochemistry  69, 356-64

Hicks LM, Cahoon RE, Bonner ER, Rivard RS, Sheffield J, Jez JM (2007) Thiol-based regulation of redox-active glutamate-cysteine ligase from Arabidopsis thalianaPlant Cell  19, 2653-61

Herrera K, Cahoon RE, Kumaran S, Jez JM (2007) Reaction mechanism of glutathione synthetase from Arabidopsis thaliana: site-directed mutagenesis of active site residues.  J Biol Chem  282, 17157-65

Brendza KM, Haakenson W, Cahoon RE, Hicks LM, Palavalli LH, Chiapelli B, McLaird M, McCarter JP, Williams DJ, Hresko MC, Jez JM (2007) Phosphoethanolamine N-methyltransferase (PMT-1) catalyzes the first reaction of a new pathway for phosphocholine biosynthesis in Caenorhabditis elegans.  Biochem  J 404, 439-48

Zhang Y, Li SZ, Pan X, Cahoon RE, Jaworski JG, Wang X, Jez JM, Chen F, Yu O (2006) Using unnatural protein fusions to engineer resveratrol biosynthesis in yeast and mammalian cells.  J Am Chem Soc 128, 13030-1

Romanyuk ND, Rigden DJ, Vatamaniuk OK, Lang A, Cahoon RE, Jez JM, Rea PA (2006) Mutagenic definition of papain-like catalytic triad and sufficiency of N-terminal domain for single-site enzyme acylation and core catalysis by an eukaryotic phytochelatin synthase.  Plant Physiol 141, 858-69

Phartiyal P, Kim WS, Cahoon RE, Jez JM, Krishnan HB (2006) Soybean ATP sulfurylase, a homodimeric enzyme involved in sulfur assimilation, is abundantly expressed in roots and induced by cold treatment.  Arch Biochem Biophys 450, 20-9

Palavalli LH, Brendza KM, Haakenson W, Cahoon RE, McLaird M, Hicks LM, McCarter JP, Williams DJ, Hresko MC, Jez JM (2006) Defining the role of phosphomethylethanolamine N-methyltransferase from Caenorhabditis elegans in phosphocholine biosynthesis by biochemical and kinetic analysis.  Biochemistry 45, 6056-65

Bonner ER, Cahoon RE, Knapke SM, Jez JM (2005) Molecular basis of plant cysteine biosynthesis: structural and functional analysis of O-acetylserine sulfhydrylase from Arabidopsis thalianaJ Biol Chem 280, 38803-13

Jez JM, Cahoon RE (2004) Kinetic mechanism of glutathione synthetase from Arabidopsis thaliana.  J Biol Chem 279, 42726-42731

Jez JM, Cahoon RE, Chen S (2004) Arabidopsis thaliana glutamate-cysteine ligase: functional properties, kinetic mechanism, and regulation of activity.  J Biol Chem 279, 33463-70