Sangaralingam Kumaran

Sangaralingam Kumaran

Postdoctoral Associate, 2006-2008
• Associate Professor, National Institute of Microbial Technology, Chandigarh, India

Yi H*, Dey S*, Kumaran S, Lee SG, Krishnan HB, Jez JM (2013) Structure of soybean serine acetyltransferase and formation of the cysteine regulatory complex as a molecular chaperone.  J Biol Chem 288, 36463-72

Kumaran S, Yi H, Krishnan HB, Jez JM (2009) Assembly of the cysteine synthase complex and the regulatory role of protein-protein interactions.  J Biol Chem  284, 10268-75

Kumaran S*, Schroeder AC*, Hicks LM, Cahoon RE, Halls C, Yu O, Jez JM (2008) Contributions of conserved serine and tyrosine residues to catalysis, ligand binding, and cofactor processing in the active site of tyrosine ammonia lyase.  Phytochemistry 69, 1496-506

Kumaran S, Francois JA, Krishnan HB, Jez JM  (2008) Regulatory protein-protein interactions in primary metabolism: the case of the cysteine synthase complex In Sulfur Assimilation and Abiotic Stress in Plants (NA Khan, RP Singh, Eds), pp. 97-109, Springer-Verlag, NY

Herrera K, Cahoon RE, Kumaran S, Jez JM (2007) Reaction mechanism of glutathione synthetase from Arabidopsis thaliana: site-directed mutagenesis of active site residues.  J Biol Chem  282, 17157-65

Kumaran S, Jez JM (2007) Thermodynamics of the interaction between O-acetylserine sulfhydrylase and the C-terminus of serine acetyltransferase. Biochemistry 46, 5586-94

Kumaran S*, Francois JA*, Jez JM (2006) Structural basis for interaction of O-acetylserine sulfhydrylase and serine acetyltransferase in the Arabidopsis cysteine synthase complex.  Plant Cell 18, 3647-55