Oxidation reactions are powerful tools for synthesis because they allow us to reverse the polarity of electron-rich functional groups, generate highly reactive intermediates, and increase the functionality of molecules.
The electrochem. synthesis of pyrazolidine-3,5-diones and benzoxazoles by N-N bond formation and C,O linkage, resp., represents an easy access to medicinally relevant structures. Electrochem. as a key technol.
In electrochem. processes, an oxidn. half-reaction is always paired with a redn. half-reaction. Although systems for reactions such as the redn. of CO2 can be coupled to H2O oxidn. to produce O2 at the anode, large-scale O2 prodn.
Cu(I)-catalyzed "click"-reactions cannot be performed on a borate ester derived polymer coating on a microelectrode array because the Cu(II)-precursor for the catalyst triggers background reactions between both acetylene and azide groups with the
