December 14, 2017

Hypertophic osteodystrophy in six Weimaraner puppies associated with systemic signs

In an effort to keep bloodlines of Weimaraners pure, breeders have forced Weimaraners with similar genetic makeups to produce more generations over time. As a result, several diseases have arisen, including hypertrophic osteodystrophy. Hypertrophic osteodystrophy is a disease with many symptoms including anorexia, lethargy, trouble standing and walking due to a malformation of bones in the limbs, vomiting, diarrhea, and many others. These symptoms were noticed approximately at the age of 4 months for all six dogs investigated in this study. Radiography was used to find any anatomical issues with the dogs in the limbs and chest cavity. Researchers noticed that in addition to improper bone structure in all four of the limbs, there were also signs leading them to believe that the dogs had lung problems because of the how the chest cavity was shaped.

Dogs were prescribed different forms of medication to help them cope with their ailments. The dogs were given simple non-steroidal anti-inflammatory drugs, antibiotics, or glucocorticocosteroids. Although none of the medications were fully effective on all the dogs, the glucocorticocosteroids gave the dogs the longest time without a relapse of the symptoms.  However, the researchers also noticed that in some cases, the symptoms of the disease would return 4 or 5 days if the dogs were vaccinated. Some dogs were vaccinated multiple times. In conclusion, the authors of the report state that Weimaraners should undergo a variation of the vaccination process, as there appeared to possibly be a correlation between the time of vaccination and the onset of the disease.

V Abeles, John M. Angles, Shimon Harrus, and Itamar Aroch. “Hypertophic osteodystrophy in six Weimaraner puppies associated with systemic signs.” ResearchGate: August 1999. Web.

Original Article: https://www.researchgate.net/publication/12832847_Hypertophic_osteodystrophy_in_six_Weimaraner_puppies_associated_with_systemic_signs

Summary by Ford Young