Stephen Vadia

Stephen Vadia

Postdoctoral Scientist

Current Research

Stephen is using a combination of chemical and genetic approaches to dissect the mechanisms underlying the growth rate-dependent control of cell size.


Si, F, G. Le Treut, J. T. Sauls, S. Vadia, P. A. Levin, and S.  Jun (2019) Mechanistic origin of cell-size control and homeostasis in bacteria, Current BIology, in press

McAuley, S., S. Vadia, C. Jani, A. Huynh, ‡Z. Yang, P. A. Levin, and J. Nodwell (2019) A chemical inhibitor of cell growth reduces cell size in Bacillus subtilis, ACS Chemical Biology, In press

Vadia, S., J. L. Tse, Z. Yang, R. Lucena, D. Kellogg, J. Wang, and P. A. Levin (2017) Fatty acid synthesis sets cell envelope capacity and dictates microbial cell size, Current Biology, in press.

Vadia, S. and P. A. Levin (2017) Bacterial Size: Can’t escape the long arm of the law. Curr Biol 27:R339-R341. PMID:28486115 doi: 10.1016/j.cub.2017.03.050.

Vadia, S. and P. A. Levin, (2015) Growth rate and cell size: a re-examination of the growth law, (2015) Current Opinion in Microbiology 24: 96-103. PMID: 25662920

Vadia S and Seveau S, Fluxes of Ca2+ and K+ are required for the listeriolysin O-dependent internalization pathway of Listeria monocytogenesInfect Immun. 2014 Mar;82(3):1084-91

Arnett E, Vadia S, Nackerman CC, Oghumu S, Satoskar AR, McLeish KR, Uriarte SM and Seveau S, The pore-forming toxin listeriolysin O is degraded by neutrophil metalloproteinase-8 and fails to mediate Listeria monocytogenes intracellular survival in neutrophils. J Immunol. 2014 Jan 1;192(1):234-44.

Vadia S, Arnett E, Haghighat AC, Wilson-Kubalek EM, Tweten RK and Seveau S.The pore-forming toxin listeriolysin O mediates a novel entry pathway of L. monocytogenes into human hepatocytes. PLoS Pathog. 2011 Nov;7(11):e1002356. doi: 10.1371/journal.ppat.1002356. Epub 2011 Nov 3.