Publications

Preprints

Westfall, C. S. and P. A. Levin,  (PREPRINT)  High levels of antibiotic tolerance and persistence are induced by the commercial anti-microbial triclosan, in revision. https://www.biorxiv.org/content/early/2017/06/13/090829

2018

Hill, N. S., J. Zuke, P. J. Buske, A-C Chien, and P. A. Levin (2018) A nutrient-dependent division antagonist is regulated post-translationally by the Clp proteases in Bacillus subtilisBMC Microbiol 18:29-43. PMID: 29625553 doi.org/10.1186/s12866-018-1155-2

Wehrens, M., D. Ershov, R. Rozendaal, N. Walker, D. Schultz, R. Kishony, P. A. Levin, and S. J. Tans (2018) Size Laws and Division Ring Dynamics in Filamentous Escherichia coli cells, Curr Biol 28: 1-8.  doi.org/10.1016/j.cub.2018.02.006

Westfall, C. S. and P. A. Levin (2018) Comprehensive analysis of central carbon metabolism reveals multiple connections between nutrients, biosynthetic capacity, and cell morphology in Escherichia coli, PLOS Genetics, 14(2) e1007205. doi.org/10.1371/journal.pgen.1007205

2017

Westfall, C.S. and P. A. Levin (2017) Bacterial Cell Size: Multifactorial and Multifaceted, Invited review for Annual Review of Microbiology, 71: 499-517. PMID: 28886685     DOI: 10.1146/annurev-micro-090816-093803

Vadia, S., J. L. Tse, R. Lucena, D. Kellogg, J. Wang, and P. A. Levin (2017) Fatty acid synthesis sets cell envelope capacity and dictates microbial cell size, Current Biology 27 (12):1757 - 1767.e5 PMID: 28602657 DOI: http://dx.doi.org/10.1016/j.cub.2017.05.076

Subject of Dispatch in Current Biology, Willis, L. and K. C. Huang (2017) Cell Size: Fat makes cells fat 27(12) R592 -R594  PMID:28633027   DOI: http://dx.doi.org/10.1016/j.cub.2017.05.017

Vadia, S. and P. A. Levin (2017) Bacterial Size: Can’t escape the long arm of the law. Curr Biol 27:R339-R341. PMID:28486115  DOI: 10.1016/j.cub.2017.03.050.

den Blaauwen, T., L. W. Hamoen, and P. A. Levin (2017) The Divisome at 25: The road ahead, Curr Opin Microbiol 36:85–94  PMID: 28254403  DOI:10.1016/j.mib.2017.01.001 

2015

Arjes, H.A., B. Lai, E. R. Emelue, A. Steinbach, and P. A. Levin (2015) Mutations in the bacterial cell division protein FtsZ highlight the role of GTP binding and longitudinal subunit interactions in assembly and function. BMC Microbiology, 5:209 DOI 10.1186/s12866-015-0544-z.

Levin, P. A. and E. R. Angert, Small but mighty: cell size and bacteria (2015) invited chapter for Cold Spring Harbor Perspectives: Size Control in Biology, from Organelles to Organisms. Edited by Drs. Rebecca Heald, Iswar Hariharan, and David Wake, 7(7):a019216. doi: 10.1101/cshperspect.a019216. PMID:26054743

Land, A.D., P. Hogan, S. Fritz and P. A. Levin, (2015) Phenotypic variation is almost entirely independent of the host-pathogen relationship in clinical isolates of S. aureus, PLoS ONE, 10(6):e0129670. doi: 10.1371/journal.pone.0129670. PMID: 26098551

Vadia, S. and P. A. Levin, (2015) Growth rate and cell size: a re-examination of the growth law, (2015) Current Opinion in Microbiology 24: 96-103. PMID: 25662920

Taheri-Araghi, S, S. Bradde, J. T. Sauls, N. S. Hill, P. A. Levin, J. Paulsson, M. Vergassola, and S. Jun. (2015) Cell-size control and homeostasis in bacteria, Current Biology 25 (3), 385-391PMID: 25544609.

Buske, P. J., A. Mittal, R. V. Pappu, and P. A. Levin (2015) An intrinsically disordered linker plays a critical role in bacterial cell division, Seminars in Cell and Developmental Biology 37, 3-10. PMID: 25305578.

2014

Arjes, H. A. , A. Kriel, N. A. Sorto, J. T. Shaw, J. D. Wang and P.  A. Levin. (2014) Failsafe mechanisms couple division and DNA replication in bacteria, Current Biology. 24(18): 2149-2155. DOI: 10.1016/j.cub.2014.07.055. 

Subject of Dispatch in Current Biology, K. Jonas (2015) Cell Cycle: Once Out, Never in AgainCurrent Biology 24(18): R841-R843DOI: 10.1016/j.cub.2014.07.067.

Land, A. D., Q, Luo, and P. A. Levin (2014) Functional domain analysis of the cell division inhibitor EzrA, PLoS ONE  9(7): e102616. doi:10.1371/journal.pone.0102616.  (PDF)

2013

Hill, N. S., P. J. Buske, Y. Shi, and P. A. Levin. (2013) A moonlighting enzyme links Escherichia coli cell size with central metabolism, PLoS Genetics 9(7): e1003663.doi:10.1371/journal.pgen.10036. 6. (PDF)

Buske, P. J. and P. A. Levin. (2013) A flexible C-terminal linker is required for proper FtsZ assembly in vitro and cytokinetic ring formation in vivo, Mol. Microbiol. 2:249-263. PMID: 23692518 (PDF)

2012

Chien, A-C, S. K. Zareh, Y. M. Wang and P. A. Levin. (2012) Changes in the oligomerization potential of the division inhibitor UgtP coordinate Bacillus subtilis cell size with nutrient availability, Mol. Microbiol. 86:594-610. PMID: 22931116 (PDF)

Chien, A-C., N. S. Hill and P. A. Levin. (2012) Cell size control in bacteria, Current Biology, 22(9):R340-R349 (PDF)

Hill, N. S., R. Kadoya, D. K. Chattoraj, and P. A. Levin. (2012), Cell size and the initiation of DNA replication in bacteria, PLoS Genet 8(3): e1002549.doi:10.1371/journal.pgen.1002549. (PDF)

Subject of Research Highlight in Nature Reviews Microbiology, Cellular microbiology: Replication comes in all sizes, Nature Reviews Microbiology 10, 312-313. Doi:10.1038/nrmicro2793. (PDF)

Buske, P. J. and P. A. Levin. (2012) The extreme C-terminus of the bacterial cytoskeletal protein FtsZ plays a fundamental role in assembly independent of modulatory proteins, J. Biol. Chem., 287:10945-10957.(PDF)

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