Publications

Publications at Washington University

 

38. Rana, M.; Cho, H. J.; Roy, T. K.; Mirica, L. M.; Sharma, A. K.; "Azo-dyes based small bifunctional molecules for metal chelation and controlling amyloid formation", Inorg. Chim. Acta2018471, 419-429. DOI: 10.1016/j.ica.2017.11.029.

37. Tang, F.; Park, S. V.; Rath, N. P.; Mirica, L. M.; "Electronic versus steric effects of pyridinophane ligands on Pd(III) complexes", Dalton Trans.201847, 1151-1158. DOI: 10.1039/C7DT04366J.

36. Sharma, A. K.; Schultz, J. W. Prior, J. T.; Rath, N. P.; Mirica, L. M.; "Coordination Chemistry of Bifunctional Chemical Agents Designed for Applications in 64Cu PET Imaging for Alzheimer's Disease", Inorg. Chem.201756 (22), 13801-13814. DOI10.1021/acs.inorgchem.7b01883.

35. Wessel, A. J.; Schultz, J. W.; Tang, F.; Duan, H.; Mirica, L. M.*; "Improved synthesis of symmetrically & asymmetrically N-substituted pyridinophane derivatives", Org. Biomol. Chem., 2017, 46, 9923-9931. DOI: 10.1039/C7Ob02508D.

34.  Bandara, N.;# Sharma, A. K.;# Krieger, S.; Schultz, J. W.; Han, B. H.; Rogers, B. E.;* Mirica, L. M.;* “Evaluation of 64Cu-Based Radiopharmaceuticals that Target Aβ Peptide Aggregates as Diagnostic Tools for Alzheimer’s Disease”, J. Am. Chem. Soc., 2017, 139, 12550-12558, DOI: 10.1021/jacs.7b05937.

33.  Fuchigami, K.; Rath, N. P.; Mirica, L. M.* “Mononuclear Rhodium(II) and Iridium(II) Complexes Supported by Tetradentate Pyridinophane Ligands”, Inorg. Chem., 2017, 56, 9404-9408, DOI: 10.1021/acs.inorgchem.7b01619.

32. Cascella, B.; Lee, S. G.; Singh, S.; Jez, J. M.;* Mirica, L. M.* "The small molecule JIB-04 disrupts O2 binding in the Fe-dependent histone demethylase KDM4A/JMJD2A" Chem. Comm. 2017, 53, 2174-2177; DOI: 10.1039/c6cc09882g. 

31. Mendez, D. L.; Babbitt, S. E.; King, J. D.; D'Alessandro, J.; Watson, M. B.; Blankenship, R. E.; Mirica, L. M.; Kranz, R. G.* "Engineered holocytochrome c synthases that biosynthesize new cytochromes c" Proc. Natl. Acad. Sci. U. S. A. 2017, 114, 2235-2240, DOI: 10.1073/pnas.1615929114.

30. Watson, M. B.; Rath, N. P.; Mirica, L. M. "Oxidative C-C Bond Formation Reactivity of Organometallic Ni(II), Ni(III), and Ni(IV) Complexes", J. Am. Chem. Soc., 2017, 139, 35-38, DOI: 10.1021/jacs.6b10303.

29. Schultz, J. W.; Fuchigami, K.; Zheng, B.; Rath, N. P.; Mirica, L. M. "Isolated Organometallic Nickel(III) and Nickel(IV) Complexes Relevant to Carbon-Carbon Bond Formation Reactions", J. Am. Chem. Soc., 2016, 138, 12928-12934, DOI: 10.1021/jacs.6b06862.

28. Zhou, W.; Watson, M. B.; Zheng, S.; Rath, N. P.; Mirica, L. M. "Ligand effects on the properties of Ni(III) complexes: aerobically-induced aromatic cyanation at room temperature", Dalton Trans., 2016, 137, 15886-15893, DOI: 10.1039/C6DT02185A

27. Orf, G. S.; Saer, R. G.; Niedzwiedzki, D. M.;p Zhang, H.; McIntosh, C. L.; Schultz, J. W.; Mirica, L. M.; Blankenship R. E.* "Evidence for a cysteine-mediated mechanism of excitation energy regulation in a photosynthetic antenna complex" Proc. Natl. Acad. Sci. U. S. A., 2016, 113, E4486-4493, DOI: 10.1073/pnas.1603330113. 

26. Pedrick, Ea. A.; Schultz, J. W.; Wu, G.; Mirica, L. M.; Hayton, T. W.* "Perturbation of the O-U-O Angle in Uranyl by Coordination to a 12-Membered Macrocycle", Inorg. Chem., 2016, 55, 5693-5701; DOI: 10.1021/acs.inorgchem.6b00799

25. Zhou, W.; Zheng, S.; Schultz, J.; Rath, N. P.; Mirica, L. M. "Aromatic Cyanoalkylation through Double C-H Activation Mediated by Ni(III)", J. Am. Chem. Soc., 2016DOI: 10.1021/jacs.6b02405

24. Zhou, W.; Rath, N. P.; Mirica, L. M. M. "Oxidatively-induced aromatic cyanation mediated by Ni(III)", Dalton Trans., 2016, DOI: 10.1039/C6DT00064A

23. Zhou, W.; Schultz, J. W.; Rath, N. P.; Mirica, L. M. "Aromatic Methoxylation and Hydroxylation by Organometallic High-Valent Nickel Complexes", J. Am. Chem. Soc., 2015, 137, 7604-7607; DOI: 10.1021/jacs.5b04082

22. Tang, F.; Rath, N. P.; Mirica, L. M. "Stable bis(trifluoromethyl)nickel(III) complexes", Chem. Commun., 2015, 51, 3113-3116; DOI: 10.1039/c4cc09594d.

21. Khusnutdinova, J. R.; Rath, N. P.; Mirica, L. M.* "The Conformational Flexibility of the Tetradentate Ligand tBuN4 is Essential for the Stabilization of (tBuN4)PdIII Complexes", Inorg. Chem., 2014, 53, 13112-13129, DOI: 10.1021/ic5023054. 

20. Sharma, A. K.; Kim, J.; Prior, J. T.; Hawco, N. J.; Rath, N. P.; Kim, J.; Mirica, L. M.*; "Small Bifunctional Chelators that Do Not Disaggregate Amyloid β Fibrils Exhibit Reduced Cellular Toxicity", Inorg. Chem., 201453, 11367-11376, DOI: 10.1021/ic500926c.

19. Zheng, B.; Tang, F.; Luo, J.; Schultz, J. W.; Rath, N. P.; Mirica, L. M.* “Organometallic Nickel(III) Complexes Relevant to Cross-Coupling and Carbon-Heteroatom Bond Formation Reactions”, J. Am. Chem. Soc., 2014, 136, 6499-6504; DOI: 10.1021/ja5024749.

18. Qu, F.; Khusnutdinova, J. R.; Rath, N. P.; Mirica, L. M.* “An Organometallic Pd(IV)-OH Complex Formed upon Aerobic Oxidation of a Pd(II) Precursor and Its C-O Bond Formation Reactivity”, Chem. Comm., 2014, 50, 3036-3039; DOI: 10.1039/c3cc49387c.

17. Sharma, A. K.; Pavlova, S. T.; Kim, J.; Kim, J.; Mirica, L. M.;* “The Effect of Cu2+ and Zn2+ on the Ab42 Peptide Aggregation and Cellular Toxicity”, Metallomics, 2013, 5, 1519-1536; DOI: 10.1039/c3mt00161j.

16. Zhang, Y.; Rempel, D. L.; Zhang, J.; Sharma, A. K.; Mirica, L. M.;* Gross M. L.* “Pulsed hydrogen-deuterium exchange mass spectrometry probes conformational changes in amyloid beta (Aβ) peptide aggregation”, Proc. Natl. Acad. Sci. U. S. A., 2013, 110, 14604-14609; DOI: 10.1073/pnas.1309175110.

15. Khusnutdinova, J. R.; Mirica, L. M.* “Organometallic Pd(III) Complexes in C-C and C-Heteroatom Bond Formation Reactions”, invited book chapter in C-H Activation and Functionalization, Transition Metal Mediation, Royal Society of Chemistry, 2013.

14. Luo, J.; Rath, N. P.; Mirica, L. M.* “Oxidative Reactivity of (N2S2)PdRX Complexes (R = Me, Cl; X = Me, Cl, Br): Involvement of Palladium(III) and Palladium(IV) Intermediate”, Organometallics, 2013, 32, 3343-3353; DOI: 10.1021/om400286j.

13. Khusnutdinova, J. R.; Luo, J.; Rath, N. P.; Mirica, L. M.* “Late First Row Transition Metal Complexes of a Tetradentate Pyridinophane Ligand: Electronic Properties and Reactivity Implications”, Inorg. Chem., 2013, 52, 3920-3932, DOI: 10.1021/ic400260z.

12.  Mirica, L. M.;* Khusnutdinova, J. R., “Structure and Electronic Properties of Pd(III) Complexes”, Coord. Chem. Rev., 2013, 257, 299-314. DOI: 10.1016/j.ccr.2012.04.030.

11. Cascella, B.; Mirica, L. M.* “Kinetic Analysis of Iron-Dependent Histone Demethylases: a-Ketoglutarate Substrate Inhibition and Potential Relevance to the Regulation of Histone Demethylation in Cancer Cells”, Biochemistry, 2012, 51, 8699-8701, DOI: 10.1021/bi3012466.

10. Tang, F.; Qu, F.; Khusnutdinova, J. R.; Rath, N. P.; Mirica, L. M.* “Structural and Reactivity Comparison of Analogous Organometallic Pd(III) and Pd(IV) Complexes”, Dalton Trans., 2012, 41, 14046-14050, DOI:10.1039/C2DT32127K.

9. Tang, F.; Zhang, Y.; Rath, N. P.; Mirica, L. M.* “Detection of Pd(III) and Pd(IV) Intermediates during the Aerobic Oxidative C-C Bond Formation from a Pd(II) Dimethyl Complex”, Organometallics, 2012, 31, 6690-6696. DOI: 10.1021/om300752w.

8. Khusnutdinova, J. R.; Qu, F.; Zhang, Y.; Rath, N. P.; Mirica, L. M.* “Formation of the Pd(IV) Complex [(Me3tacn)PdIVMe3]+ through Aerobic Oxidation of (Me3tacn)PdIIMe2 (Me3tacn = N,N’,N’’-trimethyl-1,4,7-triazacyclononane)”, Organometallics, 2012, 31, 4627-4630, DOI: 10.1021/om300426r. Featured on the cover of issue 13.

7. Evangelio, E.; Rath, N. P.; Mirica, L. M.* “Cycloaddition Reactivity Studies of First Row Transition Metal-Azide Complexes and Alkynes: An Inorganic Click Reaction for Metalloenzyme Inhibitor Synthesis”, Dalton Trans., 2012, 41, 8010-8021, DOI: 10.1039/c2dt30145h. Invited contribution for the “New Talent Americas” issue.

6. Sharma, A. K.; Pavlova, S. T.; Kim, J.; Finkelstein, D.; Hawco, N. J.; Rath, N. P.; Kim, J.; Mirica, L. M.* “Bifunctional Metal-Binding Compounds for Controlling the Metal-Mediated Aggregation of the Ab42 Peptide”, J. Am. Chem. Soc., 2012, 134, 6625-6636, DOI: 10.1021/ja210588m.

5.  Khusnutdinova, J. R.; Rath, N. P.; Mirica, L. M.* “The Aerobic Oxidation of a Pd(II) Dimethyl Complex Leads to Selective Ethane Elimination from a Pd(III) Intermediate”, J. Am. Chem. Soc., 2012, 134, 2414-2422, DOI: 10.1021/ja210841f.

4. Luo, J.; Khusnutdinova, J. R.; Rath, N. P.; Mirica, L. M.* “Unsupported d8-d8 Interactions in Cationic PdII and PtII Complexes: Evidence for a Significant Metal-Metal Bonding Character”, Chem. Comm., 2012, 48, 1532-1534, DOI: 10.1039/c1cc15420f. Invited contribution for the “Emerging Investigators” issue.

3. Luo, J.; Rath, N. P.; Mirica, L. M.* “Dinuclear Co(II)Co(III) Mixed-Valence and Co(III)Co(III) Complexes with N- and O- Donor Ligands: Characterization and Water Oxidation Studies”, Inorg. Chem., 2011, 50, 6152-6157, DOI: 10.1021/ic201031s.

2. Khusnutdinova, J. R.; Rath, N. P.; Mirica, L. M.* "Dinuclear Pd(III) Complexes with a Single Unsupported Bridging Halide Ligand: Reversible Formation from Mononuclear Pd(II) or Pd(IV) Precursors", Angew. Chem. Int. Ed., 2011, 50, 5532-5536, DOI: 10.1002/anie.201100928.

1.  Khusnutdinova, J. R.; Rath, N. P.; Mirica, L. M.* “Stable Mononuclear Organometallic Pd(III) Complexes and Their C-C Bond Formation Reactivity”, J. Am. Chem. Soc., 2010, 132, 7303-7305; DOI: 10.1021/ja103001g. Featured as “News of the Week” in Chem. & Eng. News, 2010, 88, 21, 9.

Publications from Postdoctoral and Ph.D. Studies

16. Verma, P.; Weir, J.; Mirica, L. M.; Stack, T. D. P.* “Tale of a Twist: Magnetic and Optical Switching in Copper(II) Semiquinone Complexes”, Inorg. Chem., 2011, 50, 9816-9825.

15. Op’t Holt, B. T.; Vance, M. A.; Mirica, L. M.; Heppner, D. E.; Stack, T. D. P.,* Solomon E. I.* “Reaction Coordinate of a Functional Model of Tyrosinase: Spectroscopic and Computational Characterization”, J. Am. Chem. Soc., 2009, 131, 6421-6438.

14. Humphreys, K. J.; Mirica, L. M.; Wang Y.; Klinman, J. P.* “Galactose Oxidase as a Model for Reactivity at a Copper Superoxide Center”, J. Am. Chem. Soc., 2009, 131, 4657-4663.

13. Mirica, L. M.; McCusker, K. P.; Munos, J. W.; Liu, H. W.; Klinman, J. P.* “Probing the Nature of Reactive Fe/O2 Intermediates in Non-Heme Iron Enzymes through 18O Kinetic Isotope Effects”, J. Am. Chem. Soc., 2008, 130, 8122-8123.

12. Mirica, L. M.; Klinman, J. P.* “The Nature of O2 Activation by the Ethylene-Forming Enzyme ACC Oxidase”, Proc. Natl. Acad. Sci. U. S. A., 2008, 105, 1814-1819.

11. Welford, R. W. D.; Lam, A.; Mirica, L. M.; Klinman, J. P.* “Partial Conversion of Hansenula polymorpha Amine Oxidase into a ‘Plant’ Amine Oxidase: Implications for Copper Chemistry and Mechanism”, Biochemistry, 2007, 46, 10817-10827.

10. Thrower, J. T.; Mirica, L. M.; McCusker, K. P.; Klinman, J. P.* “Mechanistic Investigations of 1-Aminocylcyclopropane 1-Carboxylic Acid Oxidase with Alternate Cyclic and Acyclic Substrates”, Biochemistry, 2006, 45, 13108-13117.

9. Mirica, L. M.; Rudd, D. J.; Vance, M.; Solomon, E. I.;* Hedman, B.;* Hodgson, K. O.;* Stack, T. D. P.* “A m-h2:h2-Peroxodicopper(II) Complex with a Secondary Diamine Ligand: A Functional Model of Tyrosinase”, J. Am. Chem. Soc., 2006, 128, 2654-2665.

8. Cole, A. P.; Mahadevan, V.; Mirica, L. M.; Ottenwaelder, X.; Stack, T. D. P.* “Bis(m-oxo)dicopper(III) Complexes of a Homologous Series of Simple Peralkylated 1,2-Diamines: Steric Modulation of Structure, Stability, and Reactivity”, Inorg. Chem., 2005, 44, 7345-7364.

7. Yoon, J.; Mirica, L. M.; Stack, T. D. P.;* Solomon, E. I.* “Variable-Temperature Variable-Field Magnetic Circular Dichroism Studies of Tris-Hydroxy and m3-Oxo Bridged Trinuclear Cu(II) Complexes: Geometric and Electronic Structures of the Native Intermediate of Multicopper Oxidases”, J. Am. Chem. Soc., 2005, 127, 13680-13693.

6. Mirica, L. M.; Vance, M.; Rudd, D. J.; Hedman, B.;* Hodgson, K. O.;* Solomon, E. I.;* Stack, T. D. P.* “Tyrosinase Reactivity in a Model Complex: An Alternative Hydroxylation Mechanism”, Science, 2005, 308, 1890-1892. Featured as a perspective in Science, 2005, 308, 1876-1877 and a science concentrate in Chem. & Eng. News, 2005, 83, 26, 38.

5. Mirica, L. M.; Stack, T. D. P. * “A Tris(m-hydroxy)tricopper(II) Complex as a Model of the Native Intermediate in Laccase and Its Relationship to a Binuclear Analogue”, Inorg. Chem., 2005, 44, 2131-2133.

4. Pratt, R. C.; Mirica, L. M.; Stack, T. D. P.* “Snapshots of a Metamorphosing Cu(II) Ground State in a Galactose Oxidase-Inspired Complex”, Inorg. Chem., 2004, 43, 8030-8039.

3. Yoon, J.; Mirica, L. M.; Stack, T. D. P.;* Solomon, E. I.* “Spectroscopic Demonstration of a Large Antisymmetric Exchange Contribution to the Spin-Frustrated Ground State of a D3 Symmetric Hydroxy-Bridged Trinuclear Cu(II) Complex: Ground-to-Excited State Superexchange Pathways”, J. Am. Chem. Soc., 2004, 126, 12586-12595.

2. Mirica, L. M.; Ottenwaelder, X.; Stack, T. D. P.* “Structure and Spectroscopy of Copper–Dioxygen Complexes”, Chem. Rev., 2004, 104, 1013-1046.

1. Mirica, L. M.; Vance, M.; Rudd, D. J.; Hedman, B.;* Hodgson, K. O.;* Solomon, E. I.;* Stack, T. D. P.* “A Stabilized m-h2:h2-Peroxodicopper(II) Complex with a Secondary Diamine Ligand and Its Tyrosinase-like Reactivity”, J. Am. Chem. Soc. 2002, 124, 9332-9333.