February 20, 2017

Electrochemical synthesis of benzoxazoles from anilides – a new approach to employ amidyl radical intermediates

A novel electrochemical method for the synthesis of benzoxazoles from readily available anilides is reported. Various functionalities are tolerated and good yields can be achieved. By employing common electrode materials and a simple constant current protocol, this method is an attractive new alternative to conventional pathways.

Tile Gieshoff,abc  Anton Kehl,a  Dieter Schollmeyer,a  Kevin D. Moellerc  and  Siegfried R. Waldvogel

Chem. Commun., 2017,53, 2974-2977