December 1, 2000

Synthetic Applications of Anodic Electrochemistry

Kevin D. Moeller

Tetrahedron, 2000, 56(49), 9527-9554

Article Outline

1. Introduction and Background

2. Elimination and Fragmentation Reactions


2.1. Kolbe and non-Kolbe oxidations of carboxylic acids

2.2. Oxidations of amides

2.3. Oxidation of sulfur

2.4. Oxidation of alcohols and ethers

2.5. Elimination and fragmentation reactions involving aromatic rings

2.6. Oxidations of copper salts

3. Coupling Reactions Involving Anodically Generated Intermediates

3.1. Aryl–aryl coupling reactions

3.2. Aryl–olefin coupling reactions

3.3. Oxidations of 1,3-dicarbonyl derivatives

3.4. Intramolecular anodic olefin coupling reactions

3.5. Trapping of N-centered radicals and radical cations

4. Using the Anode as a Source of Strong Electrophiles, Radicals, and Electrogenerated Acids

4.1. Electrogenerated acids

4.2. Oxidation of halogens

4.3. Methylthiation reactions

4.4. Anodic oxidation of NO3

4.5. Anodic oxidation of phosphines

5. Conclusions