December 2016 – Congratulations, Neha Prasad, on your graduation! Good luck in graduate school!
September 2016 – Welcome to the Wencewicz lab, Dr. Jana Markley!
The Wencewicz Lab is part of the Department of Chemistry at Washington University in St. Louis. Established in July 2013, our main research focus is antibiotic drug discovery. The Wencewicz Lab is a truly interdisciplinary research environment merging the fields of organic chemistry, enzymology, molecular biology, and microbiology. We utilize our knowledge of organic chemistry and enzyme function to elucidate the molecular mechanisms of antibiotic action, biosynthesis, resistance, and delivery. A strong bias is placed on studying antibiotics isolated from nature. Much can be learned from these "Natural Products" whose molecular scaffolds evolved over billions of years to solve many of the puzzles behind effective antibiotics. We aim to reveal Nature's antibiotic secrets to open new frontiers in antibiotic discovery including promising new antibiotic targets, novel modes of action, unique enzymatic biosynthetic transormations, resistance mechanisms, and targeted drug delivery.
Address: Washington University in St. Louis
Department of Chemistry
Laboratory Sciences Rm 401c
Campus Box 1134
One Brookings Drive
St. Louis, MO 63130